The FDA revised the specification last year after evaluating stability data from all levothyroxine sodium products. 去年,FDA在评估了所有左甲状腺素钠产品的稳定性数据后修订了质量标准。
Determination of Content and Dissolution of Levothyroxine Sodium Tablet by RP-HPLC RP-HPLC法检测左旋甲状腺素钠片剂含量及溶出度
The drug interactions and mechanism of levothyroxine sodium with other drugs 左甲状腺素钠的药物相互作用及机制初探
CONCLUSION: The relative bioavailability of new levothyroxine sodium tablet is ( 102 ± 18)%. The new and old levothyroxine sodium tablets are bioequivalent. 结论:新配方和旧配方左甲状腺素钠片剂相对生物利用度为(102±18)%,2种配方的制剂具有生物等效性。
Clinical trial of domestic levothyroxine sodium 国产左旋甲状腺素钠临床试验研究
METHODS: 2 1 healthy male volunteers received a single oral doses of 600 μ g of levothyroxine sodium in three times cross-over clinical trial and their serum drug concentration were determined by Radioimmunoassay ( RIA). 方法:21名健康男性受试者参加了单剂量(600μg)三周期交叉试验并用放免分析法测定给药后不同时间点血清药物浓度。
Levothyroxine sodium can effectively adjust the inadequate secretion of thyroid. 左甲状腺素钠片可以有效地调整甲状腺分泌不足。
The evaluation research of quality for levothyroxine sodium tablets provides the base for revision of the quality standard. 本文的评价实验研究为该品种质量标准的修订提供了依据。